Twitter followers can be a very finicky crowd. Some will want you to be a high frequency poster and others may want a sparse amount of updates. Consistency, however, is one of the keys to building a proper audience. If you are a very opinionated person, do not pander to more popular views. While this could potentially bring in bursts of new followers, it will hurt your consistency and result in many displeased older ones. It’s better to just stick to what you’re best at.
Unless you are the funniest person alive, it’s unlikely you’re churning out comedy or entertainment gold 10 times an hour. Many users will end up unfollowing you for essentially spamming and annoying them. It can be a bit tricky finding that equilibrium; just experiment with different posting frequencies until you find a good rhythm.
Staying current is probably the most important thing you can do. The trending topics are a good tool for listening to the average audience. And twitter is a fast paced social media site that is very unforgiving to yesterday’s news.
Lastly, you have to respond to a few comments a day. If you ignore your audience completely, you will lose them.The information doesn’t stop now. Keep looking: Why I may have been wrong about Facebook